ZONEGRAN ZONISAMIDE 50MG HARD CAPSULES 56`S

Partial Seizures

Initial: 100 mg PO qDay

Titrate up by 100 mg increments q2Week to no more than 600 mg PO qDay (may divide q12hr after 1st week)

Weight Loss (Off-label)

100 mg increments q2Week to no more than 600 mg PO qDay (may divide q12hr after first week); use 600 mg/day in patients who have not lost at least 5% of their initial body weight

Dosing Modifications

Renal impairment: Slower titration and more frequent monitoring advised; not recommended if patient’s glomerular filtration rate is less than 50 mL/min

Hepatic impairment: Slower titration and more frequent monitoring advised