ACICLOVIR 400MG DISPERSIBLE TABLETS 56`S

KSh1,384.00

Aciclovir Tablets are used:

  • to treat herpes and other viral infections caused by the herpes virus (varicella zoster), such as shingles
  • to prevent recurrent attacks of herpes simplex
  • to help prevent those who have low immune systems from getting herpes infections.

Aciclovir Tablets should not be used to treat herpes simplex virus (HSV) infections in newborns and babies up to 3 months old or severe HSV infections in children with low resistance to disease.

SKU: DP22694 Category:

Treatment of herpes simplex virus (HSV) infections of the skin and mucous membranes including initial and recurrent genital herpes (excluding neonatal HSV and severe HSV infections in immunocompromised children).

Suppression of recurrent herpes simplex virus infections.

Prevention of herpes simplex virus infections in immunocompromised patients.

Treatment of herpes zoster infections.

DOSAGE

Treatment of herpes simplex infections of the skin and mucous membranes including initial and recurrent genital herpes

Adults: 200mg five times daily (usually every four hours while awake), for five days. In severe infections, duration of treatment may be extended. Aciclovir is effective only if started at the onset of symptoms.

Renal impairment: For patients with a creatinine clearance of less than 10ml per minute, reduce dosage to 200mg every 12 hours.

Elderly: dosage reduction may be required.

Children aged two to fourteen years: adult dose.

Children under two years: half the adult dose.

Suppression of recurrent herpes simplex infections

Adults: 200mg four times daily or 400mg twice daily which can be reduced to 200mg two or three times daily. Therapy should be interrupted every six to twelve months for reassessment of the condition.

Renal impairment: For patients with a creatinine clearance of less than 10ml per minute, reduce dosage to 200mg every 12 hours.

Elderly: dosage reduction may be required.

Children aged two to fourteen years: adult dose.

Children under two years: half the adult dose.

Prevention of herpes simplex infections in immunocompromised patients

Adults: 200mg four times daily for the duration of the period of risk. In severely immunocompromised patients or patients with impaired absorption from the gut, the dose may be increased to 400mg four times daily.

Renal impairment: For patients with a creatinine clearance of less than 10ml per minute, reduce dosage to 200mg every 12 hours.

Elderly: dosage reduction may be required.

Children aged two to fourteen years: adult dose.

Children under two years: half the adult dose.

Treatment of herpes zoster infections

Adults: 800mg five times daily (usually every four hours while awake) for seven days. Treatment should begin as early as possible and not later than three days after the first sign of outbreak.

Renal impairment: For patients with a creatinine clearance of 10 to 25ml per minute, reduce dosage to 800mg three to four times daily. For patients with a creatinine clearance of less than 10ml per minute, reduce dosage to 800mg twice daily.

Elderly: dosage reduction may be required.

Pregnancy

The use of aciclovir should be considered only when the potential benefits outweigh the possibility of unknown risks.

Lactation

Following oral administration of 200mg aciclovir five times a day, aciclovir has been detected in breast milk at concentrations ranging from 0.6 to 4.1 times the corresponding plasma levels. These levels would potentially expose nursing infants to aciclovir dosages of up to 0.3 mg/kg/day. Caution is therefore advised if aciclovir is to be administered to a nursing woman.

Headache, dizziness, fever, fatigue, nausea, vomiting, diarrhea, abdominal pains

aciclovir