ZYMCIN 250 TABS (Azithromycin 250 mg)

Zymcin 250mg tablets contain azithromycin, a macrolide antibiotic used to treat a wide range of bacterial infections, especially of the respiratory tract, skin, and genitourinary system. Azithromycin is valued for its once-daily dosing, excellent tissue penetration, and long half-life, allowing for shorter treatment courses compared to other antibiotics.

Indications

Zymcin 250mg is prescribed for the treatment of:

• Upper and lower respiratory tract infections (e.g. bronchitis, pneumonia, tonsillitis)

• Skin and soft tissue infections

• Otitis media

• Non-gonococcal urethritis and cervicitis (e.g. Chlamydia trachomatis)

• Traveler’s diarrhea

• Dental infections

• Typhoid fever (off-label use in some settings)

Dosage and Administration

• Adults (general):

  • 500mg once daily for 3 days or

  • 500mg on Day 1 followed by 250mg once daily for 4 more days

• STI treatment: 1g single dose

• Children: Dose based on body weight (usually 10 mg/kg/day)

• Take at least 1 hour before or 2 hours after meals

Contraindications

• Hypersensitivity to azithromycin, erythromycin, or other macrolide antibiotics

• Severe hepatic impairment

• QT prolongation or known cardiac arrhythmias (use with caution)

Use in Pregnancy and Lactation

• Pregnancy: Considered relatively safe (Category B – animal studies show no risk, but no well-controlled human studies)

• Lactation: Small amounts may pass into breast milk; no known harm in standard doses

Side Effects

Common

• Diarrhea, nausea, abdominal pain

• Headache

• Mild skin rash

Serious (Rare)

• Hepatotoxicity

• QT prolongation

• Severe allergic reactions (angioedema, anaphylaxis)

• Clostridioides difficile–associated diarrhea