INDICATIONS.
Treatment of fungal infections of the skin caused by terbinafine sensitive dermatophytes in cases of tinea corporis, tinea cruris and tinea pedis, when oral therapy is considered appropriate due to the site, severity or extent of the infection.
Treatment of onychomycosis caused by terbinafine sensitive dermatophytes.
Consideration should be given to official guidance concerning the appropriate use and prescription of antifungals.
In contrast to topical terbinafine, oral terbinafine is not effective in Pityriasis versicolor
DOSAGE.
Adults:
250 mg once daily however, the duration of treatment will vary according to the indication and the severity of the infection.
Skin Infections:
Duration of the treatment
The likely durations of treatments are as follows:
Tinea pedis (interdigital, plantar/moccasin type): 2 to 6 weeks
Tinea corporis: 2 to 4 weeks
Tinea cruris: 2 to 4 weeks
Complete resolution of the signs and symptoms of infection may not occur until several weeks after mycological cure.
Onychomycosis
The duration of treatment is usually between 6 weeks and 3 months. Treatment of 6 weeks for onychomycosis of the finger nails is generally sufficient. Regarding onychomycosis of the toe nails, a 12 week treatment is usually sufficient, although a few patients with poor nail outgrow may require a longer treatment duration (6 months or longer).
Complete resolution of the signs and symptoms of infection may not occur until several months after cessation of the treatment. This corresponds to the time needed for a healthy nail growth.
ADVERSE EFFECTS.
Rash, urticaria
Tinnitus
Abdominal distension, dyspepsia, nausea, abdominal pain, diarrhoea.
Arthralgia, myalgia
Photosensitivity reaction, photodermatosis, photosensitivity allergic reaction and polymorphic light eruption.
Fatigue
Hypoacusis, hearing impaired.
