Treatment of essential hypertension in adults.
Reduction of cardiovascular morbidity in adults with:
– manifest atherothrombotic cardiovascular disease (history of coronary heart disease, stroke, or peripheral arterial disease) or
– type 2 diabetes mellitus with documented target organ damage.
Treatment of essential hypertension
The usually effective dose is 40 mg once daily. Some patients may already benefit at a daily dose of 20 mg. In cases where the target blood pressure is not achieved, the dose of telmisartan can be increased to a maximum of 80 mg once daily. Alternatively, telmisartan may be used in combination with thiazidetype diuretics such as hydrochlorothiazide which has been shown to have an additive blood pressure lowering effect with telmisartan. When considering raising the dose, it must be borne in mind that the maximum antihypertensive effect is generally attained four to eight weeks after the start of treatment.
The recommended dose is 80 mg once daily. It is not known whether doses lower than 80 mg of telmisartan are effective in reducing cardiovascular morbidity.
When initiating telmisartan therapy for the reduction of cardiovascular morbidity, close monitoring of blood pressure is recommended, and if appropriate adjustment of medications that lower blood pressure may be necessary.
Upper respiratory tract infection
Autonomic nervous system: Impotence, increased sweating, flushing
Body as a whole: Allergy, fever, leg pain, malaise
Cardiovascular: Palpitations, dependent edema, angina pectoris, tachycardia, leg edema, abnormal ECG
Central nervous system: Insomnia, somnolence, migraine, vertigo, paresthesia, involuntary muscle contractions, hypoesthesia
Gastrointestinal: Flatulence, constipation, gastritis, vomiting, dry mouth, hemorrhoids, gastroenteritis, enteritis, gastroesophageal reflux, toothache, nonspecific gastrointestinal disorders
Metabolic: Gout, hypercholesterolemia, diabetes mellitus
Musculoskeletal: Arthritis, arthralgia, leg cramps
Psychiatric: Anxiety, depression, nervousness
Resistance mechanism: Infection, fungal infection, abscess, otitis media
Respiratory: Asthma, bronchitis, rhinitis, dyspnea, epistaxis
Skin: Dermatitis, rash, eczema, pruritus; Urinary: micturition frequency, cystitis;
Vascular: Cerebrovascular disorder
Special senses: Abnormal vision, conjunctivitis, tinnitus, earache.