STALEVO LEVODOPA CARBIDOPA ENTACAPONE 75MG/18.75MG/200MG TABS 100s

KSh25,735.00

Carbidopa/levodopa/entacapone is a dopaminergic fixed-dose combination medication that contains carbidopa, levodopa, and entacapone for the treatment of Parkinson’s disease.

SKU: DP8580 Category:

INDICATIONS.

Stalevo is indicated for the treatment of adult patients with Parkinson’s disease and end-of-dose motor fluctuations not stabilised on levodopa/dopa decarboxylase (DDC) inhibitor treatment.

DOSAGE.

Substitute an equal levodopa dose with Stalevo as patient’s dose at transfer

Maintenance: Titrate as necessary

Carbidopa should be 70-100 mg/day; not to exceed 200 mg/day

Not to exceed 8 tablets/day divided -8hr while awake

Food increases levodopa absorption

Monitor hepatic, hematopoietic, cardiovascular, renal function

ADVERSE EFFECTS.

Edema

Agitation, anxiety, ataxia, bruxism, confusion, daytime somnolence decreased attention span, dyskinesia, dystonia, euphoria, insomnia, fainting, fatigue, increased trembling of hands, insouciance, malaise, memory loss, nightmares, nervousness, restlessness, trismus, vivid dreams

Alopecia, hot flushes, increased &/or dark perspiration, skin eruptions

Abdominal pain & discomfort, burning feeling in tongue, constipation, diarrhea, dysgeusia, dry mouth, dysphagia, hiccups, meteorism, sialorrhea, nausea, weight loss.

Muscular spasms, muscular cramp

Hematuria, dark urine, incontinence, priapism, urine retention

Blurred vision, diplopia, dilated pupil, oculogyric problems

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