SOFOSVEL (SOFOSBUVIR 400MG +VELPATASVIR 100MG) TABLET

KSh7,585.00

This medication is a combination of sofosbuvir and velpatasvir and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver. It may sometimes be used with another antiviral medication (ribavirin).

SKU: DP8301 Category:

INDICATIONS.

Indicated for chronic hepatitis C virus (HCV) infection in adults with HCV genotypes 1, 2, 3, 4, 5, and 6 without cirrhosis or with compensated cirrhosis; or with decompensated cirrhosis for use in combination with ribavirin.

 

DOSAGE.

Without cirrhosis or with compensated cirrhosis (Child-Pugh A): Sofosbuvir/velpatasvir for 12 weeks

With decompensated cirrhosis (Child-Pugh B or C): Sofosbuvir/velpatasvir plus ribavirin for 12 weeks

Weight-based ribavirin dose

<75 kg: 1000 mg/day PO divided BID

≥75 kg: 1200 mg/day PO divided BID

Modify ribavirin starting dose and on-treatment dosage based on hemoglobin and creatinine clearance.

ADVERSE EFFECTS.

Fatigue

Anemia

Hemoglobin

Nausea

Headache

Insomnia

Nausea

Asthenia

Insomnia

Lipase increase

Rash

Depression

Increased creatinine kinase ≥10 x ULN

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