Description
INDICATIONS
Rybelsus is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus to improve glycaemic control as an adjunct to diet and exercise
• as monotherapy when metformin is considered inappropriate due to intolerance or contraindications.
• in combination with other medicinal products for the treatment of diabetes.
Off-label: Weight management in obese patients (under physician guidance)
DIRECTIONS FOR USE
Dosage:
Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
The starting dose of semaglutide is 3 mg once daily for one month. After one month, the dose should be increased to a maintenance dose of 7 mg once daily. After at least one month with a dose of 7 mg once daily, the dose can be increased to a maintenance dose of 14 mg once daily to further improve glycaemic control.
The recommended single daily maintenance doses are 7 mg or 14 mg.
The maximum recommended single daily dose of semaglutide is 14 mg. Rybelsus should always be used as one tablet per day. Taking more than one tablet a day should not be done to achieve the effect of a higher dose.
How to take:
Take your Rybelsus® tablet on an empty stomach after a recommended fasting period of at least 8 hours.
Swallow your Rybelsus® tablet whole with a sip of water (up to 120 ml). Do not split, crush or chew the tablet, as it is not known if it affects absorption of semaglutide.
After taking your Rybelsus® tablet wait at least 30 minutes before eating, drinking or taking other oral medicines. Waiting less than 30 minutes lowers the absorption of semaglutide.
SIDE EFFECTS
Nausea, vomiting, diarrhea, constipation, abdominal pain, decreased appetite, fatigue, headache, dizziness, indigestion, burping, injection site reactions, flatulence, increased heart rate
PREGNANCY AND LACTATION
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
ACTIVE INGREDIENTS
Each tablet contains 14 mg semaglutide