Hedrin?s efficacy is a result of its active ingredients, Dimethicone and Activdiol . The ingredients have been shown to be effective at killing head lice in clinical trials and even work on lice that have developed a resistance to traditional pesticide treatments. Head lice have a unique strategy of water management. Instead of producing urine they eliminate excess water via tiny passages in their exoskeleton called spiracles. The active ingredient Dimeticone, a silicone oil, disrupts this process of water management by coating the lice, causing them to become permanently immobile, and blocking the spiracles preventing them from getting rid of excess water. As a result, any lice that have recently fed suffer from death by gut rupture and, the ones that haven?t, die of starvation.

Like all insects, head lice are covered by a waxy protective coating. It is this waxy layer that helps the louse maintain its delicate internal water balance, preventing too much water from evaporating.

The Activdiol in Hedrin works dissolving away this waxy cuticle, causing death by dehydration.

Because Dimethicone and Activdiol kill lice with a ?physical? mode of action unlike a traditional chemical pesticide, you can use them as often as you like without the danger of the lice becoming resistant. Hedrin products are also free from solvents that can cause problems in some asthma sufferers.


Apply sufficient lotion to cover dry hair from base to tip; ensuring no part of the scalp is left uncovered.

Work into the hair, spreading the liquid evenly from roots to ends, and allow to dry naturally.

Wash out after a minimum of eight hours, rinsing thoroughly with water.

Repeat treatment after seven days.



For external use only.

Should be left to dry for at least 8 hours or overnight.

Keep hair away from sources of ignition, especially naked flames and burning cigarettes, whilst being treated with Hedrin 4% lotion.

Treated hair can readily burn if ignited.


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