FLAGYL METRONIDAZOLE 400MG TABLETS

Flagyl 400mg tablets contain metronidazole, a nitroimidazole antimicrobial effective against anaerobic bacteria and protozoa. It is commonly used in the treatment of gastrointestinal, gynecological, dental, and systemic infections, especially those involving anaerobic organisms. Flagyl is prescription-only and should be used under medical supervision.

Indications

Flagyl is indicated for the treatment of:

• Anaerobic bacterial infections (intra-abdominal, pelvic, brain abscesses)

• Bacterial vaginosis and trichomoniasis

• Giardiasis and amebiasis

• Helicobacter pylori eradication (as part of combination therapy)

• Dental infections

• Surgical prophylaxis in anaerobic contamination risk

Dosage and Administration

Dosage must be determined by a healthcare professional.

• Adults (typical oral dose):

  • 400–800 mg 2–3 times daily, depending on infection

  • For anaerobic infections: 400mg every 8 hours for 7–10 days

  • For trichomoniasis: 2g single dose or 400mg twice daily for 5–7 days

• Children: Dose adjusted by weight and indication

• Take with food to reduce gastrointestinal discomfort

• Do not consume alcohol during treatment and for 48 hours after

Contraindications

• Known hypersensitivity to metronidazole or nitroimidazole derivatives

• First trimester of pregnancy (unless clearly necessary)

• Severe hepatic impairment (dose adjustment may be required)

Use in Pregnancy and Lactation

• Pregnancy: Use only if clearly needed, particularly avoided in the first trimester

• Lactation: Metronidazole passes into breast milk; short-term therapy may require temporary cessation of breastfeeding

Side Effects

Common

• Metallic taste

• Nausea, vomiting

• Headache

• Diarrhea or abdominal cramps

Serious (Rare)

• Seizures, peripheral neuropathy

• Liver dysfunction

• Stevens-Johnson syndrome

• Blood disorders (e.g. leukopenia)