CAFFEINE CITRATE 10MG/ML INJECTION 10’S

KSh17,230.00

SKU: DP6697 Category:

Description

  • Caffeine is structurally related to other methylxanthines, theophylline and theobromine. It is a bronchial smooth muscle relaxant, a CNS stimulant, a cardiac muscle stimulant and a diuretic.
  • Although the mechanism of action of caffeine in apnea of prematurity is not known, several mechanisms have been hypothesized. These include:
  • (1) stimulation of the respiratory center,
  • 2) increased minute ventilation,
  • 3) decreased threshold to hypercapnia,
  • (4) increased response to hypercapnia,
  • (5) increased skeletal muscle tone, (6) decreased diaphragmatic fatigue,
  • (7) increased metabolic rate,
  • (8) increased oxygen consumption.
  • Most of these effects have been attributed to antagonism of adenosine receptors, both A1 and A2 subtypes, by caffeine, which has been demonstrated in receptor binding assays and observed at concentrations approximating those achieved therapeutically.

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